The lastest GZDoom development builds from drdteam.org (gzdoom-g4.6pre-65-g6701cd284.zip, gzdoom-g4.6pre-45-g1767fdfe7.dmg) freeze directly after launch on my Mac Mini 2020 with Apple M1 SoC (Apple Silicon / ARM64).
These builds seem to be compiled as universal apps. When I force macOS to run them through the Rosetta 2 X86 emulation layer everything seems to work fine (just launched Doom2 + Hellbound to see how map 29 runs performance wise).
Btw. GZDoom also freezes when running natively if I do not provide an iwad but then only after hitting "Quit" on the console window.