Experiment # 1 - Thieving Little Shits
Description: This uses projectiles and damagetypes to simulate pickups that both the player AND monsters can pickup.
Inspiration: Areyep's Wolf3D mods, paticularly the "greedy" secret level in which suicide troops would try to grab all the treasure before you... and would come after you once it was all gone.
In this case, it's limited to just the shotgun and zombieman as a quick example. While the pickup seemingly acts normally to the player (due to a little sleight of hand), to the zombieman it does exactly one damage (necessary for the effect to work

This could be expanded pretty easily - the main idea behind this was for monsters to use health items, but I don't think there's any way for DECORATE healing without ACS assistance, and my attention span only goes so far. Besides, why have all those guns and artifacts around your evil demonic stronghold if you aren't going to use them? Right?
Possible ideas for expansion: Enemies picking up all sorts of items - some aiding them like weapons and healing, some just to keep them away from you like a dick. Maybe have some picked up items drop from the enemy upon death? It's possible.