On high levels with Adaptive, most guns usually have Nano already (or they're Nuclear). But some mosters are partially or fully immune to some damage types, so when you have Mother-in-Law, it's also better to have AMR with 50 bullets and Zeus with 75 cells than to have Zeus with 600 cells and no powerful rifle. The Hungry usually forces to have a dedicated weapon and armor set against them (BTW try 1monster challenge wad with Nazi Replacer, Adaptive with starting 40 and everything other „Danger“, „Danger“ etc. MAP31 turns into awesome botmatch, and The Hungry is also a challenging task).
A semi-off-topic question: you seem to hit the limit of DECORATE abilities with this mod. What do you think is better: evolve DECORATE further or move the whole engine (except graph. rendering) to PicoC or QuakeC, allowing to write literally everything without complicated workaround? I'm not going to write „PicoC ZDoom“ right now, I'm just asking.