For some reason, MAP31 of Doom 2 Unleashed demonstrates particularly bad performance in GZDoom. I don't believe this is a technical issue, because it has manifested both on my desktop and laptop. The laptop (GPU = GTX 1050 Ti) is affected more severely: in both Vulkan and OpenGL I only get about 40 FPS on this map, while every other map in this WAD that I've tested so far seems to produce a stable 60 FPS (V-Sync is, of course, on). This happens without any mods, and even in no-monsters mode (but the map doesn't have a lot of monsters so they are unlikely to have too big an impact anyway).
In addition to the above, saving the game while on this map produces a significant FPS drop that lasts for a couple seconds; it is felt even on my desktop PC, which has an RTX 2080 Ti - and during normal play, even this beast of a GPU struggles to maintain a stable 60 FPS, which is evident due to the occasional screen tearing. Do note that I have no heavy post-processing effects enabled (the only one I can remember off the top of my head is bloom; SSAO is off).
Regarding the map itself, it has an above average size compared to the other maps in the WAD, and its architecture does not look overly complex. Therefore, I am unable to ascertain what exactly makes it lag so badly. I hope the developers can find out more.
Tested in GZDoom 4.2.4 and g4.3pre-522-gc5717d98d.