Bio Hazard wrote:isint that what keyconf does already? edit the cfg untill the game is shutdown?
Yes, until the game is shut down. Nothing is written to the ini. There are console commands that write to the ini. These are probably possible with the skulltag command - therefore longer lasting damage/alteration to your setup.
As for actual dangerous commands - probably none unless you happen to have a system which borks at a specific screen res or something, but PIA commands abound. Even setting up binds or something that might seem helpful could override existing stuff you have done, and what's more, still be in your ini long after the mod concerned was thrown in the recycle bin. Not such a big deal, you can easily delete/edit your ini. It's still a pain to have to re-setup things just because of a careless or malicious mod.
Here's a tip: I personally have a zdoom.ini sitting in my zdoom directory. It has all the important settings I want in it, and nothing else. If my zdoom-username.ini gets borked, I just delete it. Next time I start Zdoom, it reads my zdoom.ini - takes all the important setting from there and then writes a new zdoom-username.ini with my setup in it. The zdoom.ini is never altered, so it just sits there waiting for the next time I need to reset all my preferences.